Determinants of instantaneous pressure in canine left ventricle. Time and volume specification.

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Determinants of instantaneous pressure in canine left ventricle. Time and volume specification.

Instantaneous pressure (P) in the canine left ventricle is determined predominantly by the simultaneous volume (V) of the ventricular lumen; that is, the instantaneous P-V relation is reasonably well approximated by a regression line of isochronous pressures from different beats on the simultaneous volume values. Strictly speaking, however, the P-V data points from differently loaded contractio...

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The instantaneous isovolumic and ejecting pressure-volume relationship of the right ventricle was studied in 11 cross-circulated, isolated canine hearts to characterize the right ventricular contractile state. Accurate measurement of volume was achieved by the use of a water-filled, thin latex balloon in the right ventricle connected to a special volume loading and transducing chamber. Pressure...

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Instantaneous pressure-volume relationships and their ratio in the excised, supported canine left ventricle.

We have previously shown in the normally ejecting canine left ventricle that E(t), the time-varying ratio of instantaneous pressure, P{t), to instantaneous volume, V(t), is little affected by end-diastolic volume or aortic pressure. The present study on an excised, supported canine heart preparation indicates that the thesis on E(t) is also valid for either totally isovolumic or auxobaric beats...

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Instantaneous pressure-volume relation of the ejecting canine left atrium.

To characterize the pump function of the left atrium, we determined the instantaneous pressure-volume relation of the isolated supported left atrium. A physiologic after-loading system for the low-pressure atrium was created by coupling it to a real-time computer-simulated ventricle and a simulated venous impedance network via a volume servo-pump. In 10 atria loaded with such systems, multiple ...

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Diastolic pressure-volume relationship in the canine left ventricle.

Analysis of the passive pressure-volume filling curve of the left ventricle demonstrates that heart size and ventricular geometry exert major effects on the pressure-volume curve in the absence of changes in intrinsic muscle stiffness. Because the pressure-volume relationship is curvilinear, both quantitative and qualitative comparison of pressure-volume curves from different hearts is difficul...

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ژورنال

عنوان ژورنال: Circulation Research

سال: 1980

ISSN: 0009-7330,1524-4571

DOI: 10.1161/01.res.46.2.256